Factory supply High quality 99% tranexamic acid 1197-18-8

Factory supply High quality 99% tranexamic Acid 1197-18-8

What is Tranexamic Acid?

Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin, Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework

for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, ε-aminocaproic acid

Specification of Tranexamic Acid:

Items of Test	Limits	Results
Characteristics	White crystalline powder	Complies
Identification	Infrared absorption spectrophotometry (2.2.24)IR spectrum is in concordance with Tranexamic acid CRS	Complies
Solubility	Easy to dissolve in the water and the glacial acetic acid, difficult to dissolve in the acetone and the ethyl alcohol	Complies
PH	7.0–8.0	7.2
Chloride	≤0.014%	<0.014%
Heavy metals	≤10ppm	<10ppm
Sulfated ash	≤0.1%	<0.1%
Related substances (HPLC)	Impurity A : ≤0.1%	<0.1%
Impurity B : ≤0.2%	<0.2%	Impurity B : ≤0.2%
All other impurity : ≤0.2%	<0.2%
Assay	99.0%–101.0%	99.6%

Functions of Tranexamic Acid:

1.Menstrual bleeding

Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules.Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.

Tranexamic acid is used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.

2.Orthopedic Surgery

Tranexamic acid is used in orthopedic surgery to reduce bloodloss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.

3.Trauma

Tranexamic acid should be considered for use in bleeding trauma patients.

Application of Tranexamic Acid:

1.Menstrual bleeding of Pure Tranexamic Acid
2.Orthopedic Surgery of Pure Tranexamic Acid
3.Trauma of Pure Tranexamic Acid
4.Dentistry of Pure Tranexamic Acid
5.In obstetrics, tranexamic acid is used after delivery to reduce bleeding, often with
6.In cardiac surgery, e.g. coronary artery bypass surgery, it is used to prevent excessive blood loss.
7.Whitening effect.Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%

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Product Categories : Organic Intermediate > Pharmaceutical Intermediates